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CS-W001157 4
Total: USD 88.00

1H-Imidazo[4,5-c]pyridin-4-ol

  • CAS No. 3243-24-1

  • Cat. No. CS-0005529
  • Purity≥97%
  • MDL No.MFCD16879067

*For research and further manufacturing use only, not for direct human use.

1H-Imidazo[4,5-c]pyridin-4-ol|CS-0005529

Structure of 3243-24-1

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General Information

  • CAS No. 3243-24-1
  • Cat. No. CS-0005529
  • Purity ≥97%
  • MDL No. MFCD16879067
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅N₃O
  • Molecular Weight 135.12
  • Synonym(s) imidazopyridine-4-one
  • SMILES O=C1C(NC=N2)=C2C=CN1

Description

1H-Imidazo[4,5-c]pyridin-4-ol is a heterocyclic scaffold featuring a fused imidazo-pyridinol core with inherent hydrogen-bonding capability. This electron-rich system integrates readily into bioactive molecule design, offering enhanced solubility and metabolic stability in medicinal chemistry applications.

Application

1H-Imidazo[4,5-c]pyridin-4-ol serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through established coupling and functionalization protocols. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate efficient access to complex architectures. The molecule functions as a key intermediate in the development of kinase inhibitors and other pharmacologically relevant compounds, supporting robust synthetic workflows in both academic and industrial R&D settings.

Synthesis

  • Route1
    • null|null
      91184-02-0
    • ~57%
    • In-stock
      1H-Imidazo[4,5-c]pyridin-4-ol|CS-0005529
      3243-24-1

    References

    • Crey-Desbiolles, Caroline; Lhomme, Jean; Dumy, Pascal; Kotera, Mitsuharu Journal of the American Chemical Society, 2004 , vol. 126, # 31 p. 9532 - 9533
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 126, # 31 p. 9532 - 9533
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 126, # 31 p. 9532 - 9533

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   61.54
  • LogP   0.2512
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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