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Structure of 324-94-7
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4'-Fluoro-[1,1'-biphenyl]-4-ol features a fluoro-substituted aryl group paired with a phenolic hydroxyl, enabling direct coupling in Suzuki-Miyaura and Ullmann reactions. This bench-stable scaffold integrates readily into bioactive molecules, offering enhanced metabolic stability and controlled electron density for medicinal chemistry applications.
4'-Fluoro-[1,1'-biphenyl]-4-ol serves as a versatile building block in medicinal chemistry, enabling efficient Suzuki-Miyaura coupling due to its ortho-fluorinated aryl halide functionality. The phenolic hydroxyl group provides a handle for derivatization and metal complexation, while the biphenyl scaffold offers rigidity and π-stacking potential. Bench-stable and compatible with diverse reaction conditions, it facilitates rapid access to functionalized biaryl scaffolds relevant to pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: