Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Bromo-6-fluoronaphthalene

  • CAS No. 324-41-4

  • Cat. No. CS-W003642
  • Purity≥96%
  • MDL No.MFCD09763683

*For research and further manufacturing use only, not for direct human use.

2-Bromo-6-fluoronaphthalene|CS-W003642

Structure of 324-41-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 324-41-4
  • Cat. No. CS-W003642
  • Purity ≥96%
  • MDL No. MFCD09763683
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₆BrF
  • Molecular Weight 225.06
  • Synonym(s) 2-fluoro-6-bromonaphthalene
  • SMILES BrC1=CC=C2C=C(F)C=CC2=C1

Description

2-Bromo-6-fluoronaphthalene is a halogenated naphthalene derivative featuring complementary reactive sites for cross-coupling and functionalization. The bromine at position 2 enables palladium-catalyzed coupling, while the fluorine at position 6 offers orthogonal reactivity and enhanced metabolic stability. This dual functionality supports efficient synthesis of complex aromatic architectures in medicinal chemistry and materials science.

Application

2-Bromo-6-fluoronaphthalene serves as a versatile building block in cross-coupling reactions, enabling efficient C–C bond formation under palladium catalysis. Its ortho-halogenated naphthalene framework provides excellent regiocontrol and functional group tolerance, facilitating the synthesis of biaryl systems and complex heterocycles. The compound exhibits good bench stability and is readily purified by distillation or recrystallization, making it well-suited for scalable medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry, , vol. 8, # 8 p. 1925 - 1930
  • Route2
    • null|null
      87700-58-1
    • ~40%
    • In-stock
      2-Bromo-6-fluoronaphthalene|CS-W003642
      324-41-4

    References

    • NOVARTIS AG; ALLAN, Martin; CHAMOIN, Sylvie; HU, Qi-Ying; IMASE, Hidetomo; PAPILLON, Julien Patent: WO2011/61168 A1, 2011 ; Location in patent: Page/Page column 53 ; WO 2011/061168 A1
  • Route3

    References

    • Bioorganic and Medicinal Chemistry, , vol. 8, # 8 p. 1925 - 1930

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   0
  • LogP   3.7414
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Bromo-6-fluoronaphthalene sigma2-Bromo-6-fluoronaphthalene manufacturer2-Bromo-6-fluoronaphthalene price2-Bromo-6-fluoronaphthalene structure2-Bromo-6-fluoronaphthalene SDSbuy 2-Bromo-6-fluoronaphthalene2-Bromo-6-fluoronaphthalene supplier2-Bromo-6-fluoronaphthalene uses2-Bromo-6-fluoronaphthalene molecular weightprice of 2-Bromo-6-fluoronaphthalene2-Bromo-6-fluoronaphthalene chemical name formula of 2-Bromo-6-fluoronaphthalene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label