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1,2-Dilauroyl-sn-glycero-3-PG sodium

  • CAS No. 322647-27-8

  • Cat. No. CS-0375351
  • Molecule weight632.74
  • Purity≥98%
  • MDL No.MFCD00674289

*For research and further manufacturing use only, not for direct human use.

1,2-Dilauroyl-sn-glycero-3-PG sodium|CS-0375351

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General Information

  • CAS No. 322647-27-8
  • Cat. No. CS-0375351
  • Purity ≥98%
  • MDL No. MFCD00674289
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₅₈NaO₁₀P
  • Molecular Weight 632.74
  • Synonym(s) 1,2-Didodecanoyl-sn-glycero-3-phospho-(1′racglycerol) (sodium)
  • SMILES OCC(O)COP(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(O[Na])=O

Description

Intercalating into bacterial membrane bilayers, 12:0 PG (CAS 322647-27-8) disrupts lipid packing via its anionic sn-glycero-3-phospho-(1′-rac-glycerol) moiety and odd-numbered lauroyl acyl chains, altering permeability in Gram-positive models.

Application

12:0 PG (CAS 322647-27-8) drives monomolecular film studies by mimicking eukaryotic membrane architecture to probe NSAID-induced lipid perturbations across diverse bilayer systems. It enables precise membrane mimicry. Researchers deploy this phospholipid to engineer liposomes for PagP folding assays and construct pyrene-labeled vesicles in real-time fusion dynamics.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   137.82
  • LogP   6.8778
  • H_Acceptors   10
  • H_Donors   2
  • Rotatable_Bonds   31

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