Pyrido[2,3-b]pyrazine

Name: Pyrido[2,3-b]pyrazine
Brand: ChemScene
Availability: InStock
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CAS No. 322-46-3
Cat. No. CS-0072745
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

Structure of 322-46-3

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Description

Pyrido[2,3-b]pyrazine is a nitrogen-rich heterocyclic scaffold featuring fused pyridine and pyrazine rings, offering enhanced electron deficiency and planar rigidity. This structure enables effective integration into functional materials and pharmaceutical intermediates, particularly in applications requiring strong π-stacking and metabolic stability.

Application

Pyrido[2,3-b]pyrazine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling the construction of bioactive molecules through established coupling and functionalization protocols. Its planar, electron-deficient structure facilitates metal-catalyzed cross-couplings and offers favorable solubility and stability for synthetic optimization. Widely used in kinase inhibitor and CNS-targeted drug discovery, it functions as a core building block with predictable reactivity and excellent compatibility in multi-step synthesis.

General Information

CAS No. 322-46-3
Cat. No. CS-0072745
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅N₃
Molecular Weight 131.13
Synonym(s) Pyridopyrazine
SMILES C12=NC=CC=C1N=CC=N2

Computational Chemistry Data

TPSA 38.67
LogP 1.0248
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazine compounds

Key Words

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Pyrido[2,3-b]pyrazine

CAS No. 322-46-3

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