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CS-W001157 4
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5-Bromo-2,3-dihydro-1H-inden-2-amine hydrobromide

  • CAS No. 321352-52-7

  • Cat. No. CS-W003235
  • Purity≥97%
  • MDL No.MFCD05663963

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2,3-dihydro-1H-inden-2-amine hydrobromide|CS-W003235

Structure of 321352-52-7

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General Information

  • CAS No. 321352-52-7
  • Cat. No. CS-W003235
  • Purity ≥97%
  • MDL No. MFCD05663963
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₁Br₂N
  • Molecular Weight 293.00
  • Synonym(s) 2-Amino-5-bromoindane Hydrobromide
  • SMILES BrC(C=C1)=CC2=C1CC(N)C2.Br

Description

5-Bromo-2,3-dihydro-1H-inden-2-amine hydrobromide features a brominated indene scaffold with a pendant amine functionality, offering enhanced solubility and stability under standard conditions. This bench-stable salt form facilitates efficient incorporation into synthetic sequences requiring nitrogen-directed functionalization or transition metal-catalyzed coupling reactions.

Application

5-Bromo-2,3-dihydro-1H-inden-2-amine hydrobromide serves as a versatile intermediate in the synthesis of biologically active indoline derivatives. Its brominated aromatic core enables efficient Pd-catalyzed cross-coupling reactions, while the secondary amine functionality offers direct access to diverse heterocyclic scaffolds. The hydrobromide salt enhances solubility and stability, facilitating handling and purification in standard organic workflows.

Safety Information

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   2.4529
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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