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CS-W001157 4
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3-Methoxy-5-methylphenol

  • CAS No. 3209-13-0

  • Cat. No. CS-0181797
  • Purity≥97%
  • MDL No.MFCD00059261

*For research and further manufacturing use only, not for direct human use.

3-Methoxy-5-methylphenol|CS-0181797

Structure of 3209-13-0

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General Information

  • CAS No. 3209-13-0
  • Cat. No. CS-0181797
  • Purity ≥97%
  • MDL No. MFCD00059261
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀O₂
  • Molecular Weight 138.16
  • Synonym(s) Orcinol Monomethyl Ether
  • SMILES OC1=CC(C)=CC(OC)=C1

Description

3-Methoxy-5-methylphenol offers a strategically positioned methoxy group and methyl substituent on the aromatic ring, delivering enhanced solubility and stability in organic synthesis. This phenolic scaffold integrates readily into functionalized intermediates for pharmaceutical and agrochemical development under standard conditions.

Application

3-Methoxy-5-methylphenol serves as a versatile phenolic building block in synthetic organic chemistry, enabling access to functionalized aromatic scaffolds through electrophilic substitution and coupling reactions. Its methoxy and methyl substituents provide orthogonal reactivity for selective derivatization, while its bench-stable nature facilitates straightforward handling and purification in multi-step syntheses.

Synthesis

  • Route1
    • In-stock
      Orcinol|CS-W008652
      504-15-4
    • null|null
      74-88-4
    • ~79%
    • In-stock
      3-Methoxy-5-methylphenol|CS-0181797
      3209-13-0

    References

    • Shanghai Institute of Materia Medica, Chinese Academy of Sciences Patent: EP2199295 A1, 2010 ; Location in patent: Page/Page column 17 ;
  • Route2

    References

    • Zeneca Limited; Zeneca Pharma S.A. Patent: US6414145 B1, 2002 ;
  • Route3

    References

    • Chemische Berichte, , vol. 36, p. 892

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   1.70922
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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