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CS-W001157 4
Total: USD 88.00

Ketoprofen impurity 1

  • CAS No. 320730-08-3

  • Cat. No. CS-0156952
  • Purity≥98%
  • MDL No.MFCD09027950

*For research and further manufacturing use only, not for direct human use.

Ketoprofen impurity 1|CS-0156952

Structure of 320730-08-3

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General Information

  • CAS No. 320730-08-3
  • Cat. No. CS-0156952
  • Purity ≥98%
  • MDL No. MFCD09027950
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀O₃
  • Molecular Weight 166.18
  • Synonym(s) None
  • SMILES C1=CC(=CC(=C1)C(=O)O)CCO

Description

3-(2-Hydroxyethyl)benzoic acid features a carboxylic acid group ortho to a hydroxyethyl side chain, enabling dual functionality for conjugation and solubility enhancement. This structure supports versatile derivatization in bioconjugation and polymer chemistry, offering improved water compatibility without compromising reactivity.

Application

3-(2-Hydroxyethyl)benzoic acid serves as a versatile building block for bioactive molecule synthesis, enabling facile derivatization via its carboxylic acid and primary alcohol functionalities. The molecule exhibits good bench stability and facilitates efficient coupling reactions, protecting group manipulations, and heterocycle formation in standard organic workflows. Its dual functionality supports modular scaffold development in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • JE IL PHARMACEUTICAL CO., LTD. Patent: WO2004/113281 A1, 2004 ; Location in patent: Page 80 ;
  • Route2
    • null|null
      124-38-9
    • ~91%
    • In-stock
      Ketoprofen impurity 1|CS-0156952
      320730-08-3

    References

    • Kudos Pharmaceuticals Ltd. Patent: US2006/135770 A1, 2006 ; Location in patent: Page/Page column 31 ; US 20060135770 A1
  • Route3
    • null|null
      124-38-9
    • In-stock
      3-Bromophenethyl alcohol|CS-W007864
      28229-69-8
    • ~%
    • In-stock
      Ketoprofen impurity 1|CS-0156952
      320730-08-3

    References

    • WO2009/77990 A1, ; Page/Page column 78 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   57.53
  • LogP   0.9196
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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