5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol

Name: 5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 32058-82-5
Cat. No. CS-0157500
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol|CS-0157500

Structure of 32058-82-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 32058-82-5
Cat. No. CS-0157500
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇N₃OS
Molecular Weight 193.23
Synonym(s) 2-(4-Aminophenyl)-1,3,4-oxadiazole-5-thione
SMILES C1=C(C=CC(=C1)N)C2=NN=C(O2)S

Description

5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol features a conjugated oxadiazole-thiol scaffold paired with an electron-rich aniline group, enabling robust coordination in metal complexation and facilitating integration into bioconjugation workflows. The pendant amine enhances solubility and reactivity in aqueous environments.

Application

5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol serves as a versatile building block for heterocyclic scaffolds in medicinal chemistry. The molecule combines an electron-rich aniline moiety with a reactive thiol group on a 1,3,4-oxadiazole core, enabling facile conjugation and metal coordination. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of functionalized analogs. Functions as a key intermediate in the development of bioactive compounds targeting kinase pathways and antimicrobial agents.

Synthesis

Route1
- In-stock
  
  94-09-7
- ~%
- In-stock
  
  32058-82-5
References
- Farmaco, , vol. 57, # 7 p. 583 - 588
Route2
- 75-15-0
- In-stock
  
  5351-17-7
- ~%
- In-stock
  
  32058-82-5
References
- Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 27, # 1-12 p. 197 - 199

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 64.94
LogP 1.6075
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Mercaptan

Building Blocks Skeleton Aromatic heterocycle compounds Oxadiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

32058-82-5 sigma32058-82-5 manufacturer32058-82-5 price32058-82-5 structure32058-82-5 SDSbuy 32058-82-532058-82-5 supplier32058-82-5 uses32058-82-5 molecular weightprice of 32058-82-532058-82-5 chemical name formula of 32058-82-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-(4-Aminophenyl)-1,3,4-oxadiazole-2-thiol

CAS No. 32058-82-5

Recommended Products