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CS-W001157 4
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N-benzyl-1-phenylethan-1-amine

  • CAS No. 3193-62-2

  • Cat. No. CS-0450945
  • Purity≥97%
  • MDL No.MFCD00078747

*For research and further manufacturing use only, not for direct human use.

N-benzyl-1-phenylethan-1-amine|CS-0450945

Structure of 3193-62-2

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General Information

  • CAS No. 3193-62-2
  • Cat. No. CS-0450945
  • Purity ≥97%
  • MDL No. MFCD00078747
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₇N
  • Molecular Weight 211.30
  • Synonym(s) N-Benzyl-1-phenylethanamine
  • SMILES CC(C1=CC=CC=C1)NCC2=CC=CC=C2

Description

N-benzyl-1-phenylethan-1-amine features a tertiary amine center flanked by aromatic and alkyl substituents, delivering enhanced solubility in organic media. This structure supports efficient coupling in amine-directed transformations, particularly in catalytic asymmetric synthesis where steric and electronic balance is critical.

Application

N-Benzyl-1-phenylethan-1-amine serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to β-amino alcohol and amine scaffolds via reductive amination or conjugate addition. Its benzylic amine functionality exhibits good bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthesis workflows. Functions effectively in transition-metal-catalyzed transformations and provides a handle for further derivatization.

Synthesis

  • Route1
    • null|null
      100-52-7
    • In-stock
      1-Phenylethanamine|CS-W013564
      618-36-0
    • ~98%
    • In-stock
      N-benzyl-1-phenylethan-1-amine|CS-0450945
      3193-62-2

    References

    • Yang, Huimin; Cui, Xinjiang; Deng, Youquan; Shi, Feng Synthetic Communications, 2014 , vol. 44, # 9 p. 1314 - 1322
  • Route2
    • null|null
      14428-98-9
    • ~98%
    • In-stock
      N-benzyl-1-phenylethan-1-amine|CS-0450945
      3193-62-2

    References

    • Tararov, Vitali I.; Kadyrov, Renat; Riermeier, Thomas H.; Fischer, Christine; Boerner, Armin Advanced Synthesis and Catalysis, 2004 , vol. 346, # 5 p. 561 - 565
  • Route3
    • In-stock
      Acetophenone|CS-0015982
      98-86-2
    • null|null
      100-46-9
    • ~96%
    • In-stock
      N-benzyl-1-phenylethan-1-amine|CS-0450945
      3193-62-2

    References

    • Saxena, Ira; Borah, Ruli; Sarma, Jadab C. Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 4 p. 503 - 504

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   3.5374
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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