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CS-W001157 4
Total: USD 88.00

Methyl 2-amino-5-fluorobenzoate

  • CAS No. 319-24-4

  • Cat. No. CS-W007783
  • Purity≥97%
  • MDL No.MFCD03791308

*For research and further manufacturing use only, not for direct human use.

Methyl 2-amino-5-fluorobenzoate|CS-W007783

Structure of 319-24-4

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General Information

  • CAS No. 319-24-4
  • Cat. No. CS-W007783
  • Purity ≥97%
  • MDL No. MFCD03791308
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈FNO₂
  • Molecular Weight 169.15
  • Synonym(s) Methyl-5-fluoroanthranilate
  • SMILES COC(=O)C1=C(N)C=CC(F)=C1

Description

Methyl 2-amino-5-fluorobenzoate features a strategically positioned amino group and fluorine atom on the aromatic ring, enabling enhanced electronic modulation and metabolic stability. This bench-stable derivative integrates readily into pharmaceutical intermediates and functional materials, offering improved solubility and reactivity under standard conditions.

Synthesis

  • Route1

    References

    • MILLENNIUM PHARMACEUTICALS, INC. Patent: WO2005/28474 A2, 2005 ; Location in patent: Page/Page column 201-202 ; WO 2005/028474 A2
  • Route2
    • null|null
      67-56-1
    • In-stock
      2-Amino-5-fluorobenzoic acid|CS-W019755
      446-08-2
    • ~43%
    • In-stock
      Methyl 2-amino-5-fluorobenzoate|CS-W007783
      319-24-4

    References

    • LABORATORIOS ALMIRALL, S.A. Patent: WO2009/21696 A1, 2009 ; Location in patent: Page/Page column 65-66 ; WO 2009/021696 A1
  • Route3
    • In-stock
      2-Amino-5-fluorobenzoic acid|CS-W019755
      446-08-2
    • null|null
      18107-18-1
    • ~%
    • In-stock
      Methyl 2-amino-5-fluorobenzoate|CS-W007783
      319-24-4

    References

    • WO2007/9774 A1, ; Page/Page column 22 ; WO 2007/009774 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.1945
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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