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CS-W001157 4
Total: USD 88.00

Ethyl L-phenylalaninate hydrochloride

  • CAS No. 3182-93-2

  • Cat. No. CS-W012971
  • Purity≥97%
  • MDL No.MFCD00012507

*For research and further manufacturing use only, not for direct human use.

Ethyl L-phenylalaninate hydrochloride|CS-W012971

Structure of 3182-93-2

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General Information

  • CAS No. 3182-93-2
  • Cat. No. CS-W012971
  • Purity ≥97%
  • MDL No. MFCD00012507
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆ClNO₂
  • Molecular Weight 229.70
  • Synonym(s) None
  • SMILES N[C@@H](CC1=CC=CC=C1)C(OCC)=O.[H]Cl

Description

Ethyl L-phenylalaninate hydrochloride is a bench-stable, moisture-tolerant amino acid ester derivative featuring a protected L-phenylalanine backbone. This crystalline salt integrates seamlessly into peptide synthesis workflows, enabling direct incorporation of phenylalanine side chains with minimal purification. The hydrochloride form enhances solubility in polar solvents and stabilizes the amine functionality during handling.

Application

Ethyl L-phenylalaninate hydrochloride serves as a stable, bench-ready chiral building block for peptide synthesis and medicinal chemistry applications. Its well-defined stereochemistry and compatibility with standard coupling protocols enable efficient incorporation into peptidomimetics and bioactive scaffolds. The hydrochloride salt enhances solubility and simplifies purification, facilitating scalable workflows in API development.

Synthesis

  • Route1
    • null|null
      64-17-5
    • L-Phenylalanine Aspartame Impurity|CS-0229723
      63-91-2
    • ~10%
    • In-stock
      Ethyl L-phenylalaninate hydrochloride|CS-W012971
      3182-93-2

    References

    • Kantharaju; Babu, Vommina V. Suresh Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 8 p. 1942 - 1944
  • Route2
    • null|null
      64-17-5
    • null|null
      121269-56-5
    • ~%
    • In-stock
      Ethyl L-phenylalaninate hydrochloride|CS-W012971
      3182-93-2

    References

    • Tetrahedron Letters, , vol. 29, # 47 p. 6079 - 6082
  • Route3
    • null|null
      100-39-0
    • ~%
    • In-stock
      Ethyl L-phenylalaninate hydrochloride|CS-W012971
      3182-93-2

    References

    • Synlett, , vol. 23, # 17 p. 2559 - 2563,5 Synlett, , vol. 23, # 17 p. 2559 - 2563

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.5413
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   4

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