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CS-W001157 4
Total: USD 88.00

3-Formyl-1h-indole-7-carboxylic acid

  • CAS No. 317854-65-2

  • Cat. No. CS-0215929
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Formyl-1h-indole-7-carboxylic acid|CS-0215929

Structure of 317854-65-2

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General Information

  • CAS No. 317854-65-2
  • Cat. No. CS-0215929
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) None
  • SMILES C1=CC2=C(C(=C1)C(=O)O)NC=C2C=O

Description

3-Formyl-1H-indole-7-carboxylic acid integrates a formyl group at the 3-position and a carboxylic acid at the 7-position of the indole core, enabling direct functionalization in heterocyclic synthesis. This bifunctional scaffold supports rapid derivatization for medicinal chemistry campaigns and materials applications requiring electron-deficient aromatic platforms.

Application

3-Formyl-1H-indole-7-carboxylic acid serves as a versatile bifunctional building block for medicinal chemistry and materials synthesis. The ortho-functionalized indole core enables direct coupling reactions via the carboxylic acid or formyl group, supporting diverse transformations including amide formation, reductive amination, and condensation with hydrazides. Its bench-stable crystalline nature and compatibility with standard purification methods facilitate reliable use in multistep syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   1.6786
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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