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CS-W001157 4
Total: USD 88.00

Dibenzo[b,f][1,4]thiazepin-11(10H)-one

  • CAS No. 3159-07-7

  • Cat. No. CS-M2280
  • Purity≥98%
  • MDL No.MFCD00901197

*For research and further manufacturing use only, not for direct human use.

Dibenzo[b,f][1,4]thiazepin-11(10H)-one|CS-M2280

Structure of 3159-07-7

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General Information

  • CAS No. 3159-07-7
  • Cat. No. CS-M2280
  • Purity ≥98%
  • MDL No. MFCD00901197
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₉NOS
  • Molecular Weight 227.28
  • Synonym(s) None
  • SMILES O=C1NC2=CC=CC=C2SC3=CC=CC=C13

Description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.Dexamethasone isonicotinate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Application

Dibenzo[b,f][1,4]thiazepin-11(10H)-one serves as a rigid, polycyclic scaffold for medicinal chemistry campaigns, enabling the construction of bioactive heterocycles through standard functionalization at the C11 position. Its stability under routine reaction conditions and tolerance to diverse transformations facilitate downstream derivatization. Functions as a key building block in the synthesis of kinase inhibitors and CNS-targeted compounds.

Synthesis

  • Route1

    References

    • Polivka; Holubek; Svatek; et al. Collection of Czechoslovak Chemical Communications, 1983 , vol. 48, # 5 p. 1465 - 1476
  • Route2
    • null|null
      13739-55-4
    • ~97%
    • In-stock
      Dibenzo[b,f][1,4]thiazepin-11(10H)-one|CS-M2280
      3159-07-7

    References

    • ELI LILLY AND COMPANY Patent: WO2005/26177 A1, 2005 ; Location in patent: Page/Page column 75 ; WO 2005/026177 A1
  • Route3
    • null|null
      111974-73-3
    • ~95%
    • In-stock
      Dibenzo[b,f][1,4]thiazepin-11(10H)-one|CS-M2280
      3159-07-7

    References

    • Mahale, Ganesh D.; Kolekar, Yogesh M.; Kumar, Ashok; Singh, Dharmendra; Kodam, Kisan M.; Waghmode, Suresh B. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2011 , vol. 50, # 9 p. 1196 - 1201

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   3.4035
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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