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Structure of 3158-71-2
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4-Cyclopropylaniline features a cyclopropyl group at the para position of aniline, delivering enhanced lipophilicity and metabolic stability. This substitution pattern imparts favorable pharmacokinetic properties while maintaining nucleophilic reactivity at the amine. The compound serves as a key scaffold in medicinal chemistry for targeted CNS-penetrant molecules and bioactive intermediates.
4-Cyclopropylaniline serves as a valuable building block in medicinal chemistry, enabling the construction of bioactive heterocycles and aromatic scaffolds. Its cyclopropyl substituent imparts favorable steric and electronic properties, enhancing metabolic stability while maintaining reactivity in standard coupling and electrophilic substitution reactions. The aniline functionality facilitates direct derivatization via acylation, diazotization, or Suzuki-Miyaura coupling, making it a practical choice for library synthesis and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: