Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(Benzyloxy)-2-bromobenzene

  • CAS No. 31575-75-4

  • Cat. No. CS-W012468
  • Purity≥97%
  • MDL No.MFCD03427006

*For research and further manufacturing use only, not for direct human use.

1-(Benzyloxy)-2-bromobenzene|CS-W012468

Structure of 31575-75-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 31575-75-4
  • Cat. No. CS-W012468
  • Purity ≥97%
  • MDL No. MFCD03427006
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₁BrO
  • Molecular Weight 263.13
  • Synonym(s) 2-Benzyloxybromobenzene
  • SMILES BrC1=CC=CC=C1OCC2=CC=CC=C2

Description

1-(Benzyloxy)-2-bromobenzene features a benzyl ether linkage flanked by a bromine atom at the ortho position, enabling direct functionalization in transition-metal-catalyzed cross-coupling reactions. This bench-stable aryl halide integrates seamlessly into complex molecular architectures under standard conditions, offering predictable regioselectivity and compatibility with diverse reaction partners.

Application

1-(Benzyloxy)-2-bromobenzene serves as a versatile ortho-brominated aryl building block for palladium-catalyzed cross-coupling reactions. The benzyloxy group provides stability and orthogonal handle for selective deprotection, while the bromide enables reliable Suzuki, Stille, and Negishi couplings. Bench-stable and readily purified by flash chromatography, it functions efficiently in constructing complex biaryl scaffolds and heterocyclic systems common in medicinal chemistry and materials synthesis.

Synthesis

  • Route1
    • null|null
      95-56-7
    • null|null
      100-39-0
    • ~99%
    • In-stock
      1-(Benzyloxy)-2-bromobenzene|CS-W012468
      31575-75-4

    References

    • Wang, Hailei; Ma, Yuping; Tian, Heng; Yu, Ajuan; Chang, Junbiao; Wu, Yangjie Tetrahedron, 2014 , vol. 70, # 16 p. 2669 - 2673
  • Route2

    References

    • Zhang, Hui; Ma, Dawei; Cao, Weiguo Synlett, 2007 , # 2 p. 243 - 246
  • Route3
    • null|null
      95-56-7
    • null|null
      100-44-7
    • ~98%
    • In-stock
      1-(Benzyloxy)-2-bromobenzene|CS-W012468
      31575-75-4

    References

    • Thede, Kai; Diedrichs, Nicole; Ragot, Jacques P. Organic Letters, 2004 , vol. 6, # 24 p. 4595 - 4597

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   9.23
  • LogP   4.0281
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-(Benzyloxy)-2-bromobenzene sigma1-(Benzyloxy)-2-bromobenzene manufacturer1-(Benzyloxy)-2-bromobenzene price1-(Benzyloxy)-2-bromobenzene structure1-(Benzyloxy)-2-bromobenzene SDSbuy 1-(Benzyloxy)-2-bromobenzene1-(Benzyloxy)-2-bromobenzene supplier1-(Benzyloxy)-2-bromobenzene uses1-(Benzyloxy)-2-bromobenzene molecular weightprice of 1-(Benzyloxy)-2-bromobenzene1-(Benzyloxy)-2-bromobenzene chemical name formula of 1-(Benzyloxy)-2-bromobenzene
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label