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Structure of 315718-06-0
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tert-Butyl ethyl(2-oxoethyl)carbamate serves as a robust, bench-stable protecting group for primary amines in peptide synthesis. This carbamate derivative features a sterically hindered tert-butyl moiety paired with an electron-deficient oxoethyl linkage, enabling selective deprotection under mild acidic conditions. The combination delivers high functional group tolerance and compatibility with diverse reaction environments.
tert-Butyl ethyl(2-oxoethyl)carbamate serves as a versatile carbamate protecting group for amines, offering enhanced stability under basic conditions and facile removal via mild acidolysis. It enables efficient N-alkylation strategies in peptide synthesis and functions effectively as a building block for heterocyclic scaffolds due to its reactive β-ketoester-like moiety. The molecule exhibits excellent bench stability, compatibility with diverse functional groups, and straightforward purification, making it well-suited for iterative synthetic sequences in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: