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Structure of 31408-23-8
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5-Phenylpyrimidin-2-amine features a conjugated pyrimidine core bearing a phenyl ring at the 5-position and an amino group at C2, delivering enhanced electron density and planarity. This structural motif enables effective integration into pharmaceutical scaffolds and functional materials. The compound exhibits robust stability under standard conditions and facilitates direct coupling in transition-metal-catalyzed transformations.
5-Phenylpyrimidin-2-amine serves as a versatile scaffold in medicinal chemistry, enabling efficient construction of heterocyclic frameworks via palladium-catalyzed cross-coupling and electrophilic substitution. Its robust bench stability and compatibility with diverse functional groups facilitate straightforward derivatization for target-focused libraries. The molecule functions as a key building block in kinase inhibitor development and other bioactive compound series.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P330-P405-P501
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Lot numbers can be found on the outside label of a product: