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CS-W001157 4
Total: USD 88.00

3,5-Dichloro-6-ethylpyrazine-2-carboxamide

  • CAS No. 313340-08-8

  • Cat. No. CS-W000778
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3,5-Dichloro-6-ethylpyrazine-2-carboxamide|CS-W000778

Structure of 313340-08-8

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General Information

  • CAS No. 313340-08-8
  • Cat. No. CS-W000778
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇Cl₂N₃O
  • Molecular Weight 220.06
  • Synonym(s) 3,5-Dichloro-6-ethylpyrazinecarboxamide
  • SMILES CCc1nc(C(N)=O)c(Cl)nc1Cl

Description

3,5-Dichloro-6-ethylpyrazine-2-carboxamide features a pyrazine core functionalized with chlorine substituents at positions 3 and 5, an ethyl group at 6, and a carboxamide at 2. This electron-deficient heterocycle integrates readily into medicinal chemistry scaffolds, offering enhanced metabolic stability and favorable binding interactions in target-directed synthesis.

Application

3,5-Dichloro-6-ethylpyrazine-2-carboxamide serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of pyrazine-based scaffolds through standard amide coupling and electrophilic substitution reactions. Its dichloro substituents provide orthogonal reactivity for late-stage functionalization, while the ethyl and carboxamide groups offer favorable solubility and stability under routine synthetic conditions. This compound facilitates the synthesis of bioactive molecules with enhanced metabolic profile and is well-suited for parallel library generation in drug discovery workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   68.87
  • LogP   1.4447
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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