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CS-W001157 4
Total: USD 88.00

2-Ethylbenzofuran

  • CAS No. 3131-63-3

  • Cat. No. CS-0141840
  • Purity≥98%
  • MDL No.MFCD00047287

*For research and further manufacturing use only, not for direct human use.

2-Ethylbenzofuran|CS-0141840

Structure of 3131-63-3

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General Information

  • CAS No. 3131-63-3
  • Cat. No. CS-0141840
  • Purity ≥98%
  • MDL No. MFCD00047287
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O
  • Molecular Weight 146.19
  • Synonym(s) Benzofuran, 2-ethyl-
  • SMILES CCC1=CC2=CC=CC=C2O1

Description

2-Ethylbenzofuran is a sterically hindered heterocyclic scaffold featuring a fused benzene and furan ring system with an ethyl substituent at the 2-position. This configuration enhances solubility in organic media while maintaining thermal stability under standard reaction conditions. The electron-rich furan moiety facilitates electrophilic substitution and enables integration into pharmaceutical intermediates and advanced materials.

Application

2-Ethylbenzofuran serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized heterocycles via electrophilic substitution and transition-metal-catalyzed coupling reactions. Its bench-stable nature and tolerance to diverse reaction conditions facilitate straightforward incorporation into complex molecular architectures.

Synthesis

  • Route1
    • null|null
      271-89-6
    • null|null
      74-96-4
    • ~82%
    • In-stock
      2-Ethylbenzofuran|CS-0141840
      3131-63-3

    References

    • Li, Hui; Pu, Shouzhi; Liu, Gang; Chen, Bing Dyes and Pigments, 2014 , vol. 101, p. 15 - 24
  • Route2

    References

    • J-PHARMA CO., LTD.; WEMPE, Michael, F.; ENDOU, Hitoshi Patent: WO2012/48058 A2, 2012 ; Location in patent: Page/Page column 13-14 ; WO 2012/048058 A2
  • Route3
    • null|null
      18448-88-9
    • ~%
    • In-stock
      2-Ethylbenzofuran|CS-0141840
      3131-63-3
    • 2-Vinyl-2,3-dihydrobenzofuran|CS-1146825
      16198-39-3

    References

    • Journal of the American Chemical Society, , vol. 103, # 9 p. 2318 - 2323

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P302+P352-P304+P340

Quality Control

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Computational Chemistry Data

  • TPSA   13.14
  • LogP   2.9952
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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