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CS-W001157 4
Total: USD 88.00

Stavudine

  • CAS No. 3056-17-5

  • Cat. No. CS-1872
  • Purity≥98%
  • MDL No.MFCD00132921

*For research and further manufacturing use only, not for direct human use.

Stavudine|CS-1872

Structure of 3056-17-5

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General Information

  • CAS No. 3056-17-5
  • Cat. No. CS-1872
  • Purity ≥98%
  • MDL No. MFCD00132921
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O₄
  • Molecular Weight None
  • Synonym(s) d4T
  • SMILES OC[C@H]1O[C@@H](N2C=C(C)C(NC2=O)=O)C=C1

Description

irregularly shaped silica gel matrix ideal for simple adsorption processes and normal-phase chromatography

Application

Stavudine serves as a nucleoside reverse transcriptase inhibitor with established utility in antiretroviral therapy. It functions as a thymidine analog, incorporating into viral DNA during reverse transcription to terminate chain elongation. The compound exhibits bench-stable properties and is employed in the synthesis of HIV-1 active pharmaceutical intermediates. Its defined reactivity profile enables reliable incorporation in oligonucleotide and nucleoside derivatization workflows.

Synthesis

  • Route1
    • null|null
      125440-17-7
    • ~98%
    • In-stock
      Stavudine|CS-1872
      3056-17-5

    References

    • Niihata; Kuno; Ebata; Matsushita Bulletin of the Chemical Society of Japan, 1995 , vol. 68, # 8 p. 2327 - 2329
  • Route2
    • ((2s,5r)-5-(5-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-2,5-dihydrofuran-2-yl)methyl acetate|CS-0671787
      77421-68-2
    • ~87%
    • In-stock
      Stavudine|CS-1872
      3056-17-5

    References

    • Mansuri; Starrett Jr.; Wos; Tortolani; Brodfuehrer; Howell; Martin Journal of Organic Chemistry, 1989 , vol. 54, # 20 p. 4780 - 4785
  • Route3
    • Zidovudine Impurity 32|CS-1004295
      5964-41-0
    • ~68%
    • In-stock
      Stavudine|CS-1872
      3056-17-5

    References

    • Ewing; Glacon; Mackenzie; Postel; Len Tetrahedron, 2003 , vol. 59, # 7 p. 941 - 945

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H341-H373
Precautionary Statements : P260-P280-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.32
  • LogP   -0.70908
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   2

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