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CS-W001157 4
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2,3,4-Trimethylpentan-3-ol

  • CAS No. 3054-92-0

  • Cat. No. CS-0215398
  • Purity≥98%
  • MDL No.MFCD00048319

*For research and further manufacturing use only, not for direct human use.

2,3,4-Trimethylpentan-3-ol|CS-0215398

Structure of 3054-92-0

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General Information

  • CAS No. 3054-92-0
  • Cat. No. CS-0215398
  • Purity ≥98%
  • MDL No. MFCD00048319
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₈O
  • Molecular Weight 130.23
  • Synonym(s) 2,3,4-trimethylpentan-2-ol
  • SMILES CC(C)C(C)(C(C)C)O

Description

This sterically hindered tertiary alcohol features a compact, branched hydrocarbon framework that confers exceptional thermal stability and low volatility. The three methyl groups surrounding the central carbon atom create a highly congested environment, minimizing unwanted side reactions during synthetic manipulations. This structural rigidity enhances its utility as a robust scaffold in organic synthesis, particularly in applications requiring resistance to dehydration or oxidation under standard conditions.

Application

2,3,4-Trimethylpentan-3-ol serves as a sterically hindered tertiary alcohol scaffold, enabling stable, high-yield transformations in protecting group chemistry and chiral auxiliaries. Its robust structure resists oxidation and dehydration under standard conditions, facilitating purification and handling in multi-step syntheses. Functions effectively as a building block for complex molecular architectures requiring controlled reactivity and enhanced stability.

Synthesis

  • Route1
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      563-80-4
    • ~%
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      598-75-4
    • In-stock
      2,3,4-Trimethylpentan-3-ol|CS-0215398
      3054-92-0

    References

    • Tetrahedron Letters, , vol. 21, p. 2171 - 2174
  • Route2
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      917-64-6
    • null|null
      565-80-0
    • ~83%
    • In-stock
      2,3,4-Trimethylpentan-3-ol|CS-0215398
      3054-92-0

    References

    • Louw, Robert; Vermeeren, Hans P.W.; Vogelzang, Martijn W. Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983 , # 12 p. 1875 - 1880
  • Route3
    • null|null
      563-80-4
    • null|null
      920-39-8
    • ~%
    • null|null
      598-75-4
    • In-stock
      2,3,4-Trimethylpentan-3-ol|CS-0215398
      3054-92-0

    References

    • Tetrahedron Letters, , vol. 21, p. 2171 - 2174

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅲ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.0494
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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