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CS-W001157 4
Total: USD 88.00

2-Chloro-6-methylnicotinic acid

  • CAS No. 30529-70-5

  • Cat. No. CS-B0702
  • Purity≥98%
  • MDL No.MFCD00134165

*For research and further manufacturing use only, not for direct human use.

2-Chloro-6-methylnicotinic acid|CS-B0702

Structure of 30529-70-5

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General Information

  • CAS No. 30529-70-5
  • Cat. No. CS-B0702
  • Purity ≥98%
  • MDL No. MFCD00134165
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆ClNO₂
  • Molecular Weight 171.58
  • Synonym(s) 2-chloro-6-methylpyridine-3-carboxylic acid
  • SMILES O=C(C1=CC=C(C)N=C1Cl)O

Description

N-Boc-N-methylethanolamine is an substituent in the synthesis of anticancer agent, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription.

Application

2-Chloro-6-methylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of substituted nicotinamide derivatives and heterocyclic scaffolds. Its orthogonal functional groups—chlorine at C2 and methyl at C6—facilitate diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and directed metalation. The compound exhibits good bench stability and compatibility with standard purification techniques, making it well-suited for iterative synthetic campaigns in API development.

Synthesis

  • Route1

    References

    • US5405826 A1, ;
  • Route2
    • In-stock
      2-Hydroxy-6-methylnicotinic acid|CS-W014340
      38116-61-9
    • ~%
    • In-stock
      2-Chloro-6-methylnicotinic acid|CS-B0702
      30529-70-5
    • null|null
      76335-91-6

    References

    • US4215123 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.74162
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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