2-Amino-4-bromobenzonitrile

Name: 2-Amino-4-bromobenzonitrile
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 304858-65-9
Cat. No. CS-W004831
Purity≥98%
MDL No.MFCD08752638

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 304858-65-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 304858-65-9
Cat. No. CS-W004831
Purity ≥98%
MDL No. MFCD08752638
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrN₂
Molecular Weight 197.03
Synonym(s) Amino-4-bromobenzonitrile
SMILES NC1=C(C#N)C=CC(=C1)Br

Description

2-Amino-4-bromobenzonitrile features a bromine substituent and nitrile group flanking a primary amine on a benzene ring, enabling direct coupling in cross-coupling reactions. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and functional materials under standard conditions.

Application

2-Amino-4-bromobenzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized heterocycles via Pd-catalyzed cross-coupling and cyclization reactions. The ortho-amino and bromo groups provide orthogonal reactivity for sequential functionalization, while the nitrile group offers compatibility with standard transformations. Bench-stable and readily purified by recrystallization, it facilitates scalable synthesis of advanced intermediates for API development.

Synthesis

Route1
- In-stock
  
  1885-29-6
- ~96%
- In-stock
  
  304858-65-9
References
- Bagheri, Mojtaba; Azizi, Najmedin; Saidi, Mohammad R. Canadian Journal of Chemistry, 2005 , vol. 83, # 2 p. 146 - 149

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 49.81
LogP 1.90298
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Cyanide/Nitrile

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

2-Amino-4-bromobenzonitrile sigma2-Amino-4-bromobenzonitrile manufacturer2-Amino-4-bromobenzonitrile price2-Amino-4-bromobenzonitrile structure2-Amino-4-bromobenzonitrile SDSbuy 2-Amino-4-bromobenzonitrile2-Amino-4-bromobenzonitrile supplier2-Amino-4-bromobenzonitrile uses2-Amino-4-bromobenzonitrile molecular weightprice of 2-Amino-4-bromobenzonitrile2-Amino-4-bromobenzonitrile chemical name formula of 2-Amino-4-bromobenzonitrile

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Amino-4-bromobenzonitrile

CAS No. 304858-65-9

Recommended Products