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CS-W001157 4
Total: USD 88.00

3-Aminophenylboronic acid

  • CAS No. 30418-59-8

  • Cat. No. CS-W018320
  • Purity≥95%
  • MDL No.MFCD00007755

*For research and further manufacturing use only, not for direct human use.

3-Aminophenylboronic acid|CS-W018320

Structure of 30418-59-8

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General Information

  • CAS No. 30418-59-8
  • Cat. No. CS-W018320
  • Purity ≥95%
  • MDL No. MFCD00007755
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈BNO₂
  • Molecular Weight 136.94
  • Synonym(s) m-Aminophenylboronic acid
  • SMILES NC1=CC=CC(B(O)O)=C1

Description

3-[2-(Cbz-amino)ethoxy]propanoic acid is a PEG linker containing an carboxylic acid (CO2H) group and a benzyl (Cbz) protecting group. The terminal carboxylic acid is reactive with primary amine groups in the presence of activators (e.g. HATU) forming a stable amide bond. The benzyl protecting group can be removed via hydrogenolysis to form a free amine. Reagent grade, for research use only.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 54, p. 4415,4418 Journal of Organic Chemistry, , vol. 2, p. 522,533
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 53, p. 713

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.48
  • LogP   -1.0514
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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