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Methyl 6-chloro-5-cyano-2-methylnicotinate

  • CAS No. 303146-25-0

  • Cat. No. CS-0367381
  • Molecule weight210.62
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 6-chloro-5-cyano-2-methylnicotinate|CS-0367381

Structure of 303146-25-0

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General Information

  • CAS No. 303146-25-0
  • Cat. No. CS-0367381
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇ClN₂O₂
  • Molecular Weight 210.62
  • Synonym(s) methyl 6-chloro-5-cyano-2-methylpyridine-3-carboxylate
  • SMILES CC1=NC(=C(C=C1C(=O)OC)C#N)Cl

Synthesis

  • Route1
    • null|null
      67-56-1
    • null|null
      919354-27-1
    • ~%
    • In-stock
      Methyl 6-chloro-5-cyano-2-methylnicotinate|CS-0367381
      303146-25-0

    References

    • ASTRAZENECA AB Patent: WO2007/8140 A1, 2007 ; Location in patent: Page/Page column 173 ; WO 2007/008140 A1
  • Route2
    • Methyl 5-cyano-6-hydroxy-2-methylnicotinate|CS-0455153
      71408-02-1
    • ~99%
    • In-stock
      Methyl 6-chloro-5-cyano-2-methylnicotinate|CS-0367381
      303146-25-0

    References

    • De Los Rios, Cristobal; Egea, Javier; Marco-Contelles, Jose; Leon, Rafael; Samadi, Abdelouahid; Iriepa, Isabel; Moraleda, Ignacio; Galvez, Enrique; Garcia, Antonio G.; Lopez, Manuela G.; Villarroya, Mercedes; Romero, Alejandro Journal of Medicinal Chemistry, 2010 , vol. 53, # 14 p. 5129 - 5143

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   62.98
  • LogP   1.7017
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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