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CS-W001157 4
Total: USD 88.00

Pyrocatechuic acid

  • CAS No. 303-38-8

  • Cat. No. CS-W019844
  • Purity≥98%
  • MDL No.MFCD00002446

*For research and further manufacturing use only, not for direct human use.

Pyrocatechuic acid|CS-W019844

Structure of 303-38-8

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General Information

  • CAS No. 303-38-8
  • Cat. No. CS-W019844
  • Purity ≥98%
  • MDL No. MFCD00002446
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆O₄
  • Molecular Weight None
  • Synonym(s) Catecholcarboxylic acid; NSC 27435
  • SMILES O=C(O)C1=CC=CC(O)=C1O

Description

2,3-Dihydroxybenzoic acid was used to study the complexes of manganese with aliphatic and aromatic polyhydroxy ligands in basic media by electrochemical, spectrophotometric and magnetic methods. It was used in isolation of new siderophore named vulnibactin from low iron cultures of Vibrio vulnificus, a human pathogen. It was used as cocrystal former to study the influence of position isomerism on the co-crystals formation and physicochemical properties of piracetam.

Application

Pyrocatechuic acid serves as a versatile ortho-dihydroxy aromatic building block, enabling selective metal chelation and oxidation-sensitive transformations. Its phenolic functionality facilitates straightforward derivatization in Suzuki-Miyaura and Ullmann couplings, while maintaining bench stability under inert conditions. Functions effectively in the synthesis of bioactive heterocycles and natural product analogs, offering predictable reactivity in standard synthetic workflows.

Synthesis

  • Route1

    References

    • LAURUS LABS PRIVATE LIMITED; MUDDULURU, Hari Krishna; MADHAVARAM, Shankar Patent: WO2014/13512 A1, 2014 ; Location in patent: Page/Page column 10-13 ;
  • Route2

    References

    • Bhujbal, Namdeo N.; Bande, Omprakash P.; Dhavale, Dilip D. Carbohydrate Research, 2009 , vol. 344, # 6 p. 734 - 738
  • Route3

    References

    • Lakouraj, Moslem Mansour; Aghajani, Bahareh; Mokhtary, Masoud Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 12 p. 2393 - 2401

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   77.76
  • LogP   0.796
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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