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CS-W001157 4
Total: USD 88.00

Dasatinib intermediate-1

  • CAS No. 302964-08-5

  • Cat. No. CS-W019750
  • Purity≥97%
  • MDL No.MFCD11045075

*For research and further manufacturing use only, not for direct human use.

Dasatinib intermediate-1|CS-W019750

Structure of 302964-08-5

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General Information

  • CAS No. 302964-08-5
  • Cat. No. CS-W019750
  • Purity ≥97%
  • MDL No. MFCD11045075
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₃Cl₂N₅OS
  • Molecular Weight 394.28
  • Synonym(s) None
  • SMILES O=C(C1=CN=C(NC2=NC(C)=NC(Cl)=C2)S1)NC3=C(C)C=CC=C3Cl

Synthesis

  • Route1
    • 4,6-Dichloro-2-methylpyrimidine Dasatinib Impurity|CS-0228905
      1780-26-3
    • In-stock
      2-Amino-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide|CS-0020987
      302964-24-5
    • ~86%
    • In-stock
      Dasatinib intermediate-1|CS-W019750
      302964-08-5

    References

    • WO2005/77945 A2, ; Page/Page column 51-52 ; WO 2005/077945 A2
  • Route2
    • null|null
      77296-31-2
    • ~73%
    • In-stock
      Dasatinib intermediate-1|CS-W019750
      302964-08-5

    References

    • WO2005/77945 A2, ; Page/Page column 52-53 ; WO 2005/077945 A2
  • Route3
    • null|null
      834888-64-1
    • ~99%
    • In-stock
      Dasatinib intermediate-1|CS-W019750
      302964-08-5

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 27 p. 6658 - 6661

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   79.8
  • LogP   4.85264
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   4

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