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Structure of 30273-11-1
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4-(sec-Butyl)aniline features a sterically hindered sec-butyl group at the para position of an aromatic amine, enhancing metabolic stability and influencing electronic properties. This substitution pattern improves solubility in organic media while maintaining reactivity in coupling processes. The molecule serves as a valuable intermediate in pharmaceutical synthesis and functional material design, where controlled steric and electronic profiles are essential.
4-(sec-Butyl)aniline serves as a versatile building block in medicinal chemistry and materials science, enabling the construction of functionalized aromatic scaffolds. Its secondary alkyl substituent provides enhanced lipophilicity and metabolic stability compared to linear analogs, while maintaining compatibility with standard coupling reactions such as Suzuki-Miyaura and Buchwald-Hartwig protocols. The molecule exhibits good bench stability, ease of purification, and tolerance to diverse reaction conditions, making it suitable for iterative synthesis and scale-up applications.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: