2-Amino-4-(4-pyridyl)-thiazole

Name: 2-Amino-4-(4-pyridyl)-thiazole
Brand: ChemScene
Availability: InStock
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CAS No. 30235-28-0
Cat. No. CS-0037808
Purity≥98%
MDL No.MFCD00490009

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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2-Amino-4-(4-pyridyl)-thiazole|CS-0037808

Structure of 30235-28-0

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Description

2-Amino-4-(4-pyridyl)-thiazole features a conjugated thiazole core linked to a pyridyl group, enabling strong electronic coupling and enhanced solubility in polar solvents. This scaffold serves as a key building block in the synthesis of functional materials, particularly in ligand design for transition metal catalysis and organic electronic applications.

Application

2-Amino-4-(4-pyridyl)-thiazole serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyridyl-thiazole scaffold provides enhanced solubility and metabolic stability, while the amino group facilitates further derivatization. The compound exhibits excellent bench stability and is compatible with common reaction conditions, making it well-suited for modular synthesis workflows in API development.

General Information

CAS No. 30235-28-0
Cat. No. CS-0037808
Purity ≥98%
MDL No. MFCD00490009
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇N₃S
Molecular Weight 177.23
Synonym(s) 4-Pyridin-4-yl-thiazol-2-ylamine
SMILES NC1=NC(C2=CC=NC=C2)=CS1

Computational Chemistry Data

TPSA 51.8
LogP 1.7873
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Amine

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Key Words

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2-Amino-4-(4-pyridyl)-thiazole

CAS No. 30235-28-0

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