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CS-W001157 4
Total: USD 88.00

2-Nitro-5-thiocyanatobenzoic acid

  • CAS No. 30211-77-9

  • Cat. No. CS-0139838
  • Purity≥98%
  • MDL No.MFCD00007139

*For research and further manufacturing use only, not for direct human use.

2-Nitro-5-thiocyanatobenzoic acid|CS-0139838

Structure of 30211-77-9

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General Information

  • CAS No. 30211-77-9
  • Cat. No. CS-0139838
  • Purity ≥98%
  • MDL No. MFCD00007139
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄N₂O₄S
  • Molecular Weight None
  • Synonym(s) NTCB
  • SMILES O=C(O)C1=CC(SC#N)=CC=C1[N+]([O-])=O

Application

2-Nitro-5-thiocyanatobenzoic acid (CAS 30211-77-9) enables site-specific conversion of cysteine to dehydroalanine in proteins, driving precise protein engineering for therapeutic development. This reaction targets reactive thiol groups with high selectivity. Researchers leverage this chemistry to map functional domains in membrane transporters, probe prion misfolding mechanisms, and synthesize bioactive recombinant peptides.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   104.23
  • LogP   1.86618
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

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