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CS-W001157 4
Total: USD 88.00

6-Isothiocyanato-Fluorescein

  • CAS No. 3012-71-3

  • Cat. No. CS-0646343
  • Purity≥90%
  • MDL No.MFCD00005063

*For research and further manufacturing use only, not for direct human use.

6-Isothiocyanato-Fluorescein|CS-0646343

Structure of 3012-71-3

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General Information

  • CAS No. 3012-71-3
  • Cat. No. CS-0646343
  • Purity ≥90%
  • MDL No. MFCD00005063
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₁₁NO₅S
  • Molecular Weight 389.38
  • Synonym(s) FITC Isomer Ⅱ
  • SMILES O=C(O)C1=CC=C(N=C=S)C=C1C2=C3C=CC(C=C3OC4=C2C=CC(O)=C4)=O

Description

6-Isothiocyanato-Fluorescein features a reactive isothiocyanate group enabling direct conjugation to primary amines under mild conditions. This fluorescent probe delivers bright emission with high quantum yield, ideal for labeling biomolecules in immunoassays and live-cell imaging.

Application

6-Isothiocyanato-Fluorescein serves as a versatile fluorescent labeling reagent, enabling efficient conjugation to primary amines under mild conditions. Its isothiocyanate group exhibits high reactivity with amine functionalities, facilitating site-specific bioconjugation in antibody–drug conjugates and protein labeling. The molecule combines strong fluorescence with excellent bench stability and straightforward purification, making it ideal for diagnostic assay development and flow cytometry applications.

Safety Information

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GHS Pictogram :
GHS No : GHS06,GHS08
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319-H334-H335
Precautionary Statements : P261-P264-P270-P271-P280-P284-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   100.1
  • LogP   4.7029
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   3

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