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CS-W001157 4
Total: USD 88.00

4-(Adamantan-1-yl)phenol

  • CAS No. 29799-07-3

  • Cat. No. CS-0096822
  • Purity≥98%
  • MDL No.MFCD00168143

*For research and further manufacturing use only, not for direct human use.

4-(Adamantan-1-yl)phenol|CS-0096822

Structure of 29799-07-3

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General Information

  • CAS No. 29799-07-3
  • Cat. No. CS-0096822
  • Purity ≥98%
  • MDL No. MFCD00168143
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₀O
  • Molecular Weight None
  • Synonym(s) 4-(tricyclo[3.3.1.1~3,7~]dec-1-yl)phenol
  • SMILES OC1=CC=C(C=C1)C23C[C@H]4C[C@@H](C3)C[C@@H](C2)C4

Description

4-(Adamantan-1-yl)phenol features a rigid, hydrophobic adamantane scaffold linked to a phenolic functional group, combining enhanced steric protection with moderate hydrogen-bonding capacity. This structural combination imparts high thermal and oxidative stability, enabling reliable integration in functional materials and bioactive molecule design under standard bench conditions.

Application

4-(Adamantan-1-yl)phenol serves as a valuable building block in medicinal chemistry and materials science, combining the rigid, hydrophobic adamantane moiety with a phenolic functional group. Its bench-stable nature and tolerance to diverse reaction conditions enable straightforward derivatization for applications in drug discovery and functional polymer synthesis.

Synthesis

  • Route1
    • null|null
      24569-89-9
    • null|null
      108-95-2
    • ~94%
    • In-stock
      4-(Adamantan-1-yl)phenol|CS-0096822
      29799-07-3

    References

    • Butov; Mokhov; Saad; Kamneva Russian Journal of Applied Chemistry, 2009 , vol. 82, # 4 p. 691 - 692
  • Route2
    • In-stock
      1-Bromoadamantane|CS-W009310
      768-90-1
    • null|null
      108-95-2
    • ~73%
    • In-stock
      4-(Adamantan-1-yl)phenol|CS-0096822
      29799-07-3

    References

    • Plachta; Starosciak Acta poloniae pharmaceutica, 1994 , vol. 51, # 1 p. 51 - 54
  • Route3

    References

    • Sasaki, Tadashi; Usuki, Arimitsu; Ohno, Masatomi Journal of Organic Chemistry, 1980 , vol. 45, # 18 p. 3559 - 3564

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅰ
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.86
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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