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CS-W001157 4
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Tetrahydro-2H-thiopyran-4-ol

  • CAS No. 29683-23-6

  • Cat. No. CS-D1275
  • Purity≥97%
  • MDL No.MFCD02942489

*For research and further manufacturing use only, not for direct human use.

Tetrahydro-2H-thiopyran-4-ol|CS-D1275

Structure of 29683-23-6

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General Information

  • CAS No. 29683-23-6
  • Cat. No. CS-D1275
  • Purity ≥97%
  • MDL No. MFCD02942489
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀OS
  • Molecular Weight 118.20
  • Synonym(s) 4-Hydroxythiane
  • SMILES OC1CCSCC1

Description

Tetrahydro-2H-thiopyran-4-ol features a saturated thiopyran ring with a hydroxyl group at the 4-position, delivering a stable, moisture-tolerant scaffold for synthetic applications. The pendant OH group enables selective derivatization, while the sulfur atom imparts moderate polarity and enhanced solubility in organic media. This compound serves as a key building block in heterocyclic synthesis, particularly in the development of bioactive molecules and functional polymers.

Application

Tetrahydro-2H-thiopyran-4-ol serves as a versatile chiral building block in synthetic organic chemistry, offering a readily accessible hydroxyl group at the C4 position of a saturated thiopyran ring. Its bench-stable nature and compatibility with standard protecting group strategies enable efficient functionalization. The molecule facilitates stereoselective transformations and functions as a key intermediate in the synthesis of sulfur-containing heterocycles and bioactive scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H318-H410
Precautionary Statements : P273-P280-P391-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.8743
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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