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CS-W001157 4
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4-(Boc-aminomethyl)-cyclohexylamine

  • CAS No. 296270-94-5

  • Cat. No. CS-0058496
  • Molecule weight228.33
  • Purity≥97%
  • MDL No.MFCD12408630

*For research and further manufacturing use only, not for direct human use.

4-(Boc-aminomethyl)-cyclohexylamine|CS-0058496

Structure of 296270-94-5

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General Information

  • CAS No. 296270-94-5
  • Cat. No. CS-0058496
  • Purity ≥97%
  • MDL No. MFCD12408630
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄N₂O₂
  • Molecular Weight 228.33
  • Synonym(s) cis-4-(Boc-aminomethyl)cyclohexylamine
  • SMILES O=C(OC(C)(C)C)NCC1CCC(N)CC1

Description

4-(Boc-aminomethyl)-cyclohexylamine features a protected primary amine tethered to a cyclohexyl ring, enabling straightforward incorporation into peptide and small-molecule scaffolds. The Boc group ensures stability during synthesis and facilitates selective deprotection under mild acidic conditions. This derivative serves as a robust building block for bioactive compound development.

Application

4-(Boc-aminomethyl)-cyclohexylamine serves as a versatile building block for the synthesis of cyclohexyl-containing pharmaceutical intermediates and bioactive molecules. The Boc-protected amine enables orthogonal functional group manipulation, while the cyclohexyl scaffold provides conformational rigidity beneficial in medicinal chemistry. This compound facilitates efficient amide coupling, reductive amination, and downstream deprotection protocols under standard laboratory conditions, offering excellent bench stability and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.0286
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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