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N-Benzyl-2-bromoacetamide

  • CAS No. 2945-03-1

  • Cat. No. CS-0661942
  • Purity≥98%
  • MDL No.MFCD00726815

*For research and further manufacturing use only, not for direct human use.

N-Benzyl-2-bromoacetamide|CS-0661942

Structure of 2945-03-1

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General Information

  • CAS No. 2945-03-1
  • Cat. No. CS-0661942
  • Purity ≥98%
  • MDL No. MFCD00726815
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀BrNO
  • Molecular Weight 228.09
  • Synonym(s) None
  • SMILES C1=CC=C(C=C1)CNC(=O)CBr

Description

N-Benzyl-2-bromoacetamide features a bromoacetyl moiety attached to a benzyl-substituted nitrogen, enabling direct incorporation into amine-functionalized substrates. This reactive electrophile facilitates site-specific conjugation in synthetic and biochemical workflows.

Application

N-Benzyl-2-bromoacetamide serves as a versatile bifunctional building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and peptide derivatives. The bromoacetyl moiety facilitates nucleophilic substitution reactions, while the N-benzyl group enhances stability and modulates reactivity. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthesis workflows and solid-phase applications.

Safety Information

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GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H311-H331-H341
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501

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Computational Chemistry Data

  • TPSA   29.1
  • LogP   1.6977
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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