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CS-W001157 4
Total: USD 88.00

4-Bromo-2-methylthiophene

  • CAS No. 29421-92-9

  • Cat. No. CS-W003194
  • Purity≥98%
  • MDL No.MFCD04116367

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2-methylthiophene|CS-W003194

Structure of 29421-92-9

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General Information

  • CAS No. 29421-92-9
  • Cat. No. CS-W003194
  • Purity ≥98%
  • MDL No. MFCD04116367
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BrS
  • Molecular Weight 177.07
  • Synonym(s) 4-BROMO-2-METHYLTHIOPHEN
  • SMILES CC1=CC(Br)=CS1

Description

n-Decane is used as a solvent as well as an internal standard in the GC analysis of oxalic, malonic and succinic acids. It is used in paint manufacture as a hydrocarbon solvent and for wood stains and varnishes as a varnish solvent. It is an active component of automotive fuels viz. gasoline (petrol).

Application

4-Bromo-2-methylthiophene serves as a versatile building block in synthetic organic chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki and Stille couplings. The bromine substituent provides high reactivity under standard conditions, while the methylthio group offers orthogonal functionalization potential. Its bench-stable nature and compatibility with diverse reaction environments make it suitable for constructing complex heterocyclic architectures and pharmaceutical intermediates.

Synthesis

  • Route1
    • null|null
      765-58-2
    • ~80%
    • In-stock
      4-Bromo-2-methylthiophene|CS-W003194
      29421-92-9

    References

    • Polyakova, Svetlana M.; Belov, Vladimir N.; Bossi, Mariano L.; Hell, Stefan W. European Journal of Organic Chemistry, 2011 , # 18 p. 3301 - 3312
  • Route2

    References

    • Polyakova, Svetlana M.; Belov, Vladimir N.; Bossi, Mariano L.; Hell, Stefan W. European Journal of Organic Chemistry, 2011 , # 18 p. 3301 - 3312

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H302-H318
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P403-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   2.81902
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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