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CS-W001157 4
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4-Hydroxythiophene-2-carbaldehyde

  • CAS No. 293742-29-7

  • Cat. No. CS-0517218
  • Molecule weight128.15
  • Purity≥98%
  • MDL No.MFCD26866790

*For research and further manufacturing use only, not for direct human use.

4-Hydroxythiophene-2-carbaldehyde|CS-0517218

Structure of 293742-29-7

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General Information

  • CAS No. 293742-29-7
  • Cat. No. CS-0517218
  • Purity ≥98%
  • MDL No. MFCD26866790
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄O₂S
  • Molecular Weight 128.15
  • Synonym(s) None
  • SMILES O=CC1=CC(O)=CS1

Description

4-Hydroxythiophene-2-carbaldehyde features a hydroxyl group adjacent to a reactive aldehyde on a thiophene scaffold, enabling direct conjugation and functionalization. This electron-rich heterocycle facilitates coupling reactions under mild conditions, offering stable access to bioactive thienyl architectures in medicinal chemistry and materials synthesis.

Application

4-Hydroxythiophene-2-carbaldehyde serves as a versatile heterocyclic building block in medicinal chemistry and synthetic organic research. The molecule combines a reactive aldehyde group with a phenolic hydroxyl, enabling facile derivatization via condensation, oxidation, or cross-coupling reactions. Its structural motif is frequently encountered in bioactive scaffolds due to favorable electronic properties and metabolic stability. Bench-stable and amenable to purification by standard chromatographic methods, it functions effectively in multi-step synthesis workflows requiring orthogonality between functional groups.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.2662
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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