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CS-W001157 4
Total: USD 88.00

5,6-Dibromonicotinic acid

  • CAS No. 29241-64-3

  • Cat. No. CS-0041188
  • Purity≥98%
  • MDL No.MFCD01927099

*For research and further manufacturing use only, not for direct human use.

5,6-Dibromonicotinic acid|CS-0041188

Structure of 29241-64-3

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General Information

  • CAS No. 29241-64-3
  • Cat. No. CS-0041188
  • Purity ≥98%
  • MDL No. MFCD01927099
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃Br₂NO₂
  • Molecular Weight 280.90
  • Synonym(s) 5,6-Dibromopyridine-3-carboxylicaci
  • SMILES O=C(C1=CC(Br)=C(Br)N=C1)O

Description

5,6-Dibromonicotinic acid is a brominated pyridine carboxylic acid featuring two adjacent bromine substituents on the aromatic ring. This configuration imparts strong electron-withdrawing character and enhances reactivity in cross-coupling processes. The molecule serves as a valuable building block for synthesizing functionalized heterocycles in medicinal chemistry and materials science.

Application

5,6-Dibromonicotinic acid serves as a versatile building block for the synthesis of brominated heterocycles and functionalized nicotinates. Its dual bromine substituents enable selective cross-coupling reactions, facilitating the construction of complex pharmaceutical scaffolds. The carboxylic acid group provides a handle for derivatization and incorporation into bioactive molecules. This compound exhibits good bench stability and compatibility with standard synthetic protocols, making it a reliable reagent in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.3048
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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