Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-(trimethylsilyl)pyridine

  • CAS No. 291312-74-8

  • Cat. No. CS-0459760
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-(trimethylsilyl)pyridine|CS-0459760

Structure of 291312-74-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 291312-74-8
  • Cat. No. CS-0459760
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂BrNSi
  • Molecular Weight 230.18
  • Synonym(s) (5-bromopyridin-2-yl)-trimethylsilane
  • SMILES BrC1=CN=C([Si](C)(C)C)C=C1

Description

5-Bromo-2-(trimethylsilyl)pyridine features a strategically positioned trimethylsilyl group that enhances stability and facilitates orthogonal functionalization. The bromine at the 5-position enables palladium-catalyzed cross-coupling reactions under mild conditions. This pyridine derivative serves as a robust building block for synthesizing complex heterocyclic architectures in medicinal chemistry and materials science.

Application

5-Bromo-2-(trimethylsilyl)pyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient late-stage functionalization of heterocyclic scaffolds. The bromine and silyl groups provide orthogonal reactivity: the bromide participates in palladium-catalyzed couplings (e.g., Suzuki, Stille), while the trimethylsilyl group offers protection and facilitates selective desilylation or further transformation. Bench-stable and compatible with standard synthetic workflows, it enables rapid diversification in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.3893
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-(trimethylsilyl)pyridine sigma5-Bromo-2-(trimethylsilyl)pyridine manufacturer5-Bromo-2-(trimethylsilyl)pyridine price5-Bromo-2-(trimethylsilyl)pyridine structure5-Bromo-2-(trimethylsilyl)pyridine SDSbuy 5-Bromo-2-(trimethylsilyl)pyridine5-Bromo-2-(trimethylsilyl)pyridine supplier5-Bromo-2-(trimethylsilyl)pyridine uses5-Bromo-2-(trimethylsilyl)pyridine molecular weightprice of 5-Bromo-2-(trimethylsilyl)pyridine5-Bromo-2-(trimethylsilyl)pyridine chemical name formula of 5-Bromo-2-(trimethylsilyl)pyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label