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CS-W001157 4
Total: USD 88.00

4-Methoxybutanoic acid

  • CAS No. 29006-02-8

  • Cat. No. CS-W001021
  • Purity≥95%
  • MDL No.MFCD00029855

*For research and further manufacturing use only, not for direct human use.

4-Methoxybutanoic acid|CS-W001021

Structure of 29006-02-8

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General Information

  • CAS No. 29006-02-8
  • Cat. No. CS-W001021
  • Purity ≥95%
  • MDL No. MFCD00029855
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₃
  • Molecular Weight 118.13
  • Synonym(s) 4-Methoxybutyric Acid
  • SMILES COCCCC(O)=O

Description

4-Methoxybutanoic acid is a γ-alkoxy carboxylic acid featuring a methoxy group at the C4 position, offering enhanced solubility and stability in polar solvents. This functionalized chain serves as a key building block for bioactive esters and polymers, enabling efficient coupling reactions under mild conditions.

Application

4-Methoxybutanoic acid serves as a versatile building block for synthesizing bioactive molecules and functional polymers. Its esterifiable carboxylic acid and methoxy-substituted aliphatic chain enable straightforward derivatization, including amidation and reduction reactions. The molecule exhibits good bench stability and facilitates purification via standard chromatographic methods. It functions effectively in coupling protocols and provides access to γ-alkoxy acid motifs found in pharmaceutical intermediates and agrochemical scaffolds.

Synthesis

  • Route1

    References

    • Schering Corporation Patent: US2006/264489 A1, 2006 ; Location in patent: Page/Page column 87 ;
  • Route2

    References

    • ARAKIS LTD. Patent: WO2005/85170 A1, 2005 ; Location in patent: Page/Page column 11-12 ;
  • Route3
    • null|null
      96-48-0
    • ~%
    • In-stock
      4-Methoxybutanoic acid|CS-W001021
      29006-02-8

    References

    • Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Patent: US4590209 A1, 1986 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P310-P312-P332+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.4976
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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