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Structure of 289483-87-0
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7-Amino-4-methyl-1H-indole-3-carbonitrile features a fused indole scaffold with strategically positioned amino, methyl, and nitrile groups. This electron-rich heterocycle integrates readily into pharmaceutical scaffolds, offering enhanced solubility and metabolic stability in synthetic intermediates. The para-nitrogen functionality enables direct coupling reactions under mild conditions.
7-Amino-4-methyl-1H-indole-3-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted indole scaffolds. Its amino and nitrile groups offer orthogonal reactivity for downstream functionalization, while the methyl substitution enhances metabolic stability. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: