Lot numbers can be found on the outside label of a product:
5-Acetyl-2-fluorobenzonitrile
-
CAS No. 288309-07-9
- Cat. No. CS-0043851
- Purity≥97%
- MDL No.MFCD09831931
*For research and further manufacturing use only, not for direct human use.
Structure of 288309-07-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 288309-07-9
- Cat. No. CS-0043851
- Purity ≥97%
- MDL No. MFCD09831931
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₆FNO
- Molecular Weight None
- Synonym(s) None
- SMILES N#CC1=CC(C(C)=O)=CC=C1F
Description
5-Acetyl-2-fluorobenzonitrile features a fluorinated aromatic ring bearing both acetyl and nitrile functionalities, enabling direct integration into pharmaceutical intermediates. The electron-deficient benzene core facilitates electrophilic substitution, while the acetyl group offers a handle for derivatization under mild conditions.
Application
5-Acetyl-2-fluorobenzonitrile serves as a versatile building block in medicinal and process chemistry, enabling efficient access to fluorinated heterocycles and functionalized aromatic scaffolds. Its orthogonal reactivity—combining an acetyl group for nucleophilic addition or enolization and a nitrile for hydrolysis or cyclization—facilitates diverse downstream transformations. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, supporting scalable synthesis of API intermediates and advanced pharmaceutical candidates.
Synthesis
-
Route1
-
97674-02-7 -
179897-89-3 - ~90%
-
In-stock
288309-07-9
References
-
AiCuris GmbH and Co. KG; Thede, Kai; Greschat, Susanne; Gericke, Kersten Matthias; Wildum, Steffen; Paulsen, Daniela Patent: US2013/45999 A1, 2013 ; Location in patent: Paragraph 0247; 0248; 0249; 0250 ;
-
-
Route2
-
960244-29-5
- ~%
-
In-stock
288309-07-9
References
-
MERCK SHARP and DOHME CORP.; PASTERNAK, Alexander; BLIZZARD, Timothy; CHOBANIAN, Harry; DE JESUS, Reynalda; DING, Fa-Xiang; DONG, Shuzhi; GUDE, Candido; KIM, Dooseop; TANG, Haifeng; WALSH, Shawn; PIO, Barbara; JIANG, Jinlong Patent: WO2013/28474 A1, 2013 ; Location in patent: Page/Page column 51 ;
-
-
Route3
-
In-stock
1007-15-4 - ~%
-
In-stock
288309-07-9
References
-
MERCK SHARP and DOHME CORP.; PASTERNAK, Alexander; BLIZZARD, Timothy; CHOBANIAN, Harry; DE JESUS, Reynalda; DING, Fa-Xiang; DONG, Shuzhi; GUDE, Candido; KIM, Dooseop; TANG, Haifeng; WALSH, Shawn; PIO, Barbara; JIANG, Jinlong Patent: WO2013/28474 A1, 2013 ; Location in patent: Page/Page column 53 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302
|
|
|
Precautionary Statements : P264-P270-P301+P310-P330-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 40.86
- LogP 1.89998
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 5-Acetyl-2-fluorobenzonitrile sigma5-Acetyl-2-fluorobenzonitrile manufacturer5-Acetyl-2-fluorobenzonitrile price5-Acetyl-2-fluorobenzonitrile structure5-Acetyl-2-fluorobenzonitrile SDSbuy 5-Acetyl-2-fluorobenzonitrile5-Acetyl-2-fluorobenzonitrile supplier5-Acetyl-2-fluorobenzonitrile uses5-Acetyl-2-fluorobenzonitrile molecular weightprice of 5-Acetyl-2-fluorobenzonitrile5-Acetyl-2-fluorobenzonitrile chemical name formula of 5-Acetyl-2-fluorobenzonitrile