Fmoc-Glu-NH2

Name: Fmoc-Glu-NH2
Brand: ChemScene
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CAS No. 288149-55-3
Cat. No. CS-0137397
Purity≥97%
MDL No.MFCD01861342

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 288149-55-3
Cat. No. CS-0137397
Purity ≥97%
MDL No. MFCD01861342
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₂₀N₂O₅
Molecular Weight 368.38
Synonym(s) (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-amino-5-oxopentanoic acid
SMILES O=C(O)CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(N)=O

Description

Fmoc-Glu-NH2 delivers a protected glutamic acid derivative with enhanced solubility and stability in aqueous and organic solvents. The fluorenylmethyloxycarbonyl (Fmoc) group enables efficient, orthogonal coupling in solid-phase peptide synthesis, while the free α-amino and side-chain carboxylate functionalities allow precise incorporation into bioactive sequences. This derivative supports robust yield and minimal racemization during chain elongation.

Application

Fmoc-Glu-NH₂ serves as a key building block in solid-phase peptide synthesis, enabling efficient incorporation of glutamic acid residues with side-chain protection. The Fmoc group ensures orthogonal deprotection under mild basic conditions, while the α-amino and side-chain carboxyl functionalities facilitate standard coupling reactions. Its bench-stable, crystalline nature supports reliable handling and purification, making it ideal for synthesizing bioactive peptides and protein conjugates.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 118.72
LogP 2.2438
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 7

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

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Fmoc-Glu-NH2

CAS No. 288149-55-3

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