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CS-W001157 4
Total: USD 88.00

Isoxazole

  • CAS No. 288-14-2

  • Cat. No. CS-W011365
  • Purity≥98%
  • MDL No.MFCD00003149

*For research and further manufacturing use only, not for direct human use.

Isoxazole|CS-W011365

Structure of 288-14-2

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General Information

  • CAS No. 288-14-2
  • Cat. No. CS-W011365
  • Purity ≥98%
  • MDL No. MFCD00003149
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₃NO
  • Molecular Weight 69.06
  • Synonym(s) None
  • SMILES C1=CON=C1

Description

Isoxazole serves as a robust heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and tunable electronic properties. This five-membered ring integrates readily into bioactive molecules, where its polarity and hydrogen-bonding capacity improve solubility and target engagement.

Synthesis

  • Route1
    • null|null
      4405-17-8
    • ~86%
    • In-stock
      Isoxazole|CS-W011365
      288-14-2

    References

    • Nitlikar, Lakshmikant H.; Shinde, Devanand B. Letters in Organic Chemistry, 2013 , vol. 10, # 9 p. 637 - 639
  • Route2

    References

    • Griesbeck, Axel G.; Franke, Marco; Neudoerfl, Joerg; Kotaka, Hidehiro Beilstein Journal of Organic Chemistry, 2011 , vol. 7, p. 127 - 134
  • Route3
    • null|null
      504-73-4
    • ~%
    • In-stock
      Isoxazole|CS-W011365
      288-14-2

    References

    • Monsanto Company Patent: US5260262 A1, 1993 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02
Signal Word : Danger
UN#: 1993
Class : 3
Packing Group : Ⅱ
Hazard Statements : H225
Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.03
  • LogP   0.6746
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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