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CS-W001157 4
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(S)-3-(Pyrrolidin-2-yl)pyridine dihydrochloride

  • CAS No. 287966-92-1

  • Cat. No. CS-0197115
  • Molecule weight221.13
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-3-(Pyrrolidin-2-yl)pyridine dihydrochloride|CS-0197115

Structure of 287966-92-1

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General Information

  • CAS No. 287966-92-1
  • Cat. No. CS-0197115
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄Cl₂N₂
  • Molecular Weight 221.13
  • Synonym(s) None
  • SMILES Cl.Cl.N1[C@@H](CCC1)C2=CN=CC=C2

Description

(S)-3-(Pyrrolidin-2-yl)pyridine dihydrochloride is a chiral heterocyclic scaffold featuring a pyrrolidine ring fused to a pyridine core, offering enhanced solubility and stability under standard conditions. This configuration enables efficient incorporation into asymmetric synthesis workflows, particularly in catalytic systems requiring defined stereochemistry. The dihydrochloride salt form improves handling and shelf life, facilitating use in medicinal chemistry and process development.

Application

(S)-3-(Pyrrolidin-2-yl)pyridine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocyclic scaffolds. Its pyridine core facilitates transition metal-catalyzed coupling reactions, while the protonated pyrrolidine nitrogen enhances solubility and crystallinity for purification. The dihydrochloride salt form ensures excellent bench stability and handling, making it ideal for high-throughput synthesis and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   2.3497
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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