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CS-W001157 4
Total: USD 88.00

1,2-Dimethylbenzimidazole

  • CAS No. 2876-08-6

  • Cat. No. CS-0196103
  • Purity≥98%
  • MDL No.MFCD00022840

*For research and further manufacturing use only, not for direct human use.

1,2-Dimethylbenzimidazole|CS-0196103

Structure of 2876-08-6

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General Information

  • CAS No. 2876-08-6
  • Cat. No. CS-0196103
  • Purity ≥98%
  • MDL No. MFCD00022840
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂
  • Molecular Weight 146.19
  • Synonym(s) None
  • SMILES CC1=NC2=C(N1C)C=CC=C2

Description

1,2-Dimethylbenzimidazole delivers a rigid, electron-rich heterocyclic scaffold ideal for coordination chemistry and catalyst design. The adjacent methyl groups enhance steric protection and stability, while the imidazole core enables strong metal binding. This compound integrates readily into ligand architectures and serves as a robust building block for functional materials.

Application

1,2-Dimethylbenzimidazole serves as a versatile heterocyclic building block in medicinal chemistry and catalysis. Its fused imidazole core exhibits enhanced stability and tunable basicity, enabling use in ligand design for transition metal complexes. The methyl groups facilitate downstream functionalization and improve solubility in organic media. This compound functions reliably in standard coupling and electrophilic substitution protocols, making it a practical scaffold for API development and synthetic intermediates.

Synthesis

  • Route1
    • null|null
      444995-68-0
    • ~92%
    • In-stock
      1,2-Dimethylbenzimidazole|CS-0196103
      2876-08-6

    References

    • Tetrahedron, , vol. 68, # 14 p. 2993 - 3000
  • Route2
    • In-stock
      2-Methyl-1H-benzo[d]imidazole|CS-W013410
      615-15-6
    • null|null
      74-88-4
    • ~99%
    • In-stock
      1,2-Dimethylbenzimidazole|CS-0196103
      2876-08-6

    References

    • Chemistry of Heterocyclic Compounds, , vol. 32, # 6 p. 672 - 681
  • Route3
    • null|null
      95-54-5
    • ~0%
    • In-stock
      2-Methyl-1H-benzo[d]imidazole|CS-W013410
      615-15-6
    • In-stock
      1,2-Dimethylbenzimidazole|CS-0196103
      2876-08-6

    References

    • US2002/28817 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.88172
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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