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CS-W001157 4
Total: USD 88.00

N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester

  • CAS No. 286961-15-7

  • Cat. No. CS-B0400
  • Purity≥95%
  • MDL No.MFCD11521562

*For research and further manufacturing use only, not for direct human use.

N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester|CS-B0400

Structure of 286961-15-7

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General Information

  • CAS No. 286961-15-7
  • Cat. No. CS-B0400
  • Purity ≥95%
  • MDL No. MFCD11521562
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₆BNO₄
  • Molecular Weight 343.23
  • Synonym(s) None
  • SMILES O=C(OCC1=CC=CC=C1)N2CC=C(CC2)B(OC(C)3C)OC3(C)C

Synthesis

  • Route1
    • In-stock
      Bis(pinacolato)diborane|CS-D1216
      73183-34-3
    • null|null
      286961-24-8
    • ~87%
    • In-stock
      N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester|CS-B0400
      286961-15-7

    References

    • Eastwood, Paul R. Tetrahedron Letters, 2000 , vol. 41, # 19 p. 3705 - 3708
  • Route2
    • In-stock
      4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine hydrochloride|CS-W021994
      1121057-75-7
    • null|null
      501-53-1
    • ~98%
    • In-stock
      N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester|CS-B0400
      286961-15-7

    References

    • INFINITY PHARMACEUTICALS, INC.; CASTRO, Alfredo, C.; EVANS, Catherine, A.; GRENIER, Louis; GROGAN, Michael, J. Patent: WO2010/118159 A1, 2010 ; Location in patent: Page/Page column 65-66 ;
  • Route3
    • null|null
      19099-93-5
    • ~%
    • In-stock
      N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester|CS-B0400
      286961-15-7

    References

    • Levell, Julian; Astles, Peter; Eastwood, Paul; Cairns, Jennifer; Houille, Olivier; Aldous, Suzanne; Merriman, Gregory; Whiteley, Brian; Pribish, James; Czekaj, Mark; Liang, Guyan; Maignan, Sebastien; Guilloteau, Jean-Pierre; Dupuy, Alain; Davidson, Jane; Harrison, Trevor; Morley, Andrew; Watson, Simon; Fenton, Garry; McCarthy, Clive; Romano, Joseph; Mathew, Rose; Engers, Darren; Gardyan, Michael; Sides, Keith; Kwong, Jennifer; Tsay, Joseph; Rebello, Sam; Shen, Liduo; Wang, Jie; Luo, Yongyi; Giardino, Odessa; Lim, Heng-Keang; Smith, Keith; Pauls, Henry Bioorganic and Medicinal Chemistry, 2005 , vol. 13, # 8 p. 2859 - 2872

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48
  • LogP   3.5867
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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