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CS-W001157 4
Total: USD 88.00

4-Acetoxy-2-azetidinone

  • CAS No. 28562-53-0

  • Cat. No. CS-W004456
  • Purity≥97%
  • MDL No.MFCD00010593

*For research and further manufacturing use only, not for direct human use.

4-Acetoxy-2-azetidinone|CS-W004456

Structure of 28562-53-0

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General Information

  • CAS No. 28562-53-0
  • Cat. No. CS-W004456
  • Purity ≥97%
  • MDL No. MFCD00010593
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₇NO₃
  • Molecular Weight 129.11
  • Synonym(s) 4-oxoazetidin-2-yl acetate
  • SMILES O=C1CC(N1)OC(=O)C

Description

4-Acetoxy-2-azetidinone features a strained four-membered β-lactam ring essential for reactivity in synthetic transformations. The acetoxy group at the 4-position enhances electrophilicity, enabling efficient coupling reactions. This bench-stable compound serves as a key intermediate in the synthesis of bioactive molecules and antibiotic analogs.

Synthesis

  • Route1
    • In-stock
      Azetidin-2-one|CS-W011364
      930-21-2
    • null|null
      64-19-7
    • ~87%
    • In-stock
      4-Acetoxy-2-azetidinone|CS-W004456
      28562-53-0

    References

    • Murahashi; Saito; Naota; Kumobayashi; Akutagawa Tetrahedron Letters, 1991 , vol. 32, # 42 p. 5991 - 5994
  • Route2
    • In-stock
      (S)-4-Oxoazetidine-2-carboxylic acid|CS-W013626
      16404-94-7
    • null|null
      64-19-7
    • ~86%
    • In-stock
      4-Acetoxy-2-azetidinone|CS-W004456
      28562-53-0

    References

    • Murahashi; Saito; Naota; Kumobayashi; Akutagawa Tetrahedron Letters, 1991 , vol. 32, # 42 p. 5991 - 5994
  • Route3
    • null|null
      53390-64-0
    • ~%
    • In-stock
      4-Acetoxy-2-azetidinone|CS-W004456
      28562-53-0

    References

    • Lee, Sang Hyup Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 1 p. 121 - 127

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS08
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H334
Precautionary Statements : P260-P261-P264-P280-P284-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.4
  • LogP   -0.6045
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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