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Structure of 28489-28-3
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4-Fluoro-3-methylpyridine features a fluorinated pyridine core with a methyl group at the 3-position, delivering enhanced electron-withdrawing character and improved metabolic stability. This combination enables efficient incorporation into pharmaceutical scaffolds, particularly in kinase inhibitors and CNS-targeted therapeutics. The molecule exhibits favorable solubility profiles and bench-stable handling under standard conditions.
4-Fluoro-3-methylpyridine serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the pyridine ring via palladium-catalyzed cross-coupling. Its fluorinated heterocyclic core offers enhanced metabolic stability and modulated electronic properties, while the methyl group provides a handle for further derivatization. Bench-stable and compatible with standard synthetic protocols, it facilitates efficient access to bioactive scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: